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ABI2 Rabbit monoclonal antibody

Product Specifications

Background

May act in regulation of cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/or ABL2. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. Regulates ABL1/c-Abl-mediated phosphorylation of MENA.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Product Name Alternative

Abelson interactor 2; ABI2; ABI2B; Abl binding protein 3; AblBP3; ArgBP1; ARGBPIA; ArgBPIB; SSH3BP2

Swiss Prot

Q9NYB9

Reactivity

Human Mouse Rat

Immunogen

A synthesized peptide derived from human ABI2

Conjugation

Unconjugated

Applications

WB IHC ICC/IF

Dilution

WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200

Purity

Affinity-chromatography

Modification

Unmodified

Molecular Weight

75kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

ABI2 Antibody detects endogenous levels of total ABI2

Applications Notes

Western blot analysis of ABI2 expression in K562 cell lysate.

Host or Source

Rabbit

Available Sizes

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