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IL-18BP, Cynomolgus (Biotinylated, HEK293, His)

The IL-18BP protein is an inhibitor of IL-18, which binds to IL-18 and prevents IL-18 from binding to its receptor, thereby inhibiting IL-18-induced IFN-γ production. IL-18BP protein is constitutively expressed and secreted in monocytes. IFN-γ can enhance the expression of this protein. IL-18BP Protein, Cynomolgus (Biotinylated, HEK293, His) is the recombinant cynomolgus-derived IL-18BP protein, expressed by HEK293 , with C-His labeled tag.

Product Specifications

Product Name Alternative

IL-18BP Protein, Cynomolgus (Biotinylated, HEK293, His), Cynomolgus, HEK293

UNSPSC

12352202

Type

Recombinant Proteins

Assay Protocol

https://www.medchemexpress.com/cytokines/il-18bp-protein-cynomolgus-biotinylated-hek293-his-solutin.html

Molecular Formula

107126419 (Gene_ID) A0A2K5UDJ4 (T28-P207) (Accession)

Molecular Weight

Approximately 50-65 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.

References & Citations

[1]Fabbi M, et al. Context-dependent role of IL-18 in cancer biology and counter-regulation by IL-18BP. J Leukoc Biol. 2015 Apr;97 (4) :665-75.|[2]Wang X, et al. Interleukin-18 and IL-18BP in inflammatory dermatological diseases. Front Immunol. 2023 Jan 18;14:955369.

Shipping Conditions

Dry ice.

Scientific Category

Recombinant Proteins

Frequently Asked Questions

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