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RING1 Rabbit monoclonal antibody

Product Specifications

Background

Constitutes one of the E3 ubiquitin-protein ligases that mediate monoubiquitination of 'Lys-119' of histone H2A, thereby playing a central role in histone code and gene regulation. H2A 'Lys-119' ubiquitination gives a specific tag for epigenetic transcriptional repression and participates in X chromosome inactivation of female mammals.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Product Name Alternative

Ring1A; Ring1; RING1A; Rnf1

Swiss Prot

Q06587

Reactivity

Human

Immunogen

A synthesized peptide derived from human RING1

Conjugation

Unconjugated

Applications

WB IHC ICC/IF

Dilution

WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200

Purity

Affinity-chromatography

Modification

Unmodified

Molecular Weight

50kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

RING1 Antibody detects endogenous levels of total RING1

Applications Notes

Western blot analysis of RING1 expression in Ramos cell lysate.

Host or Source

Rabbit

Available Sizes

Frequently Asked Questions

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