RING1 Rabbit monoclonal antibody
Product Specifications
Background
Constitutes one of the E3 ubiquitin-protein ligases that mediate monoubiquitination of 'Lys-119' of histone H2A, thereby playing a central role in histone code and gene regulation. H2A 'Lys-119' ubiquitination gives a specific tag for epigenetic transcriptional repression and participates in X chromosome inactivation of female mammals.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Product Name Alternative
Ring1A; Ring1; RING1A; Rnf1
Swiss Prot
Q06587
Reactivity
Human
Immunogen
A synthesized peptide derived from human RING1
Conjugation
Unconjugated
Applications
WB IHC ICC/IF
Dilution
WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200
Purity
Affinity-chromatography
Modification
Unmodified
Molecular Weight
50kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
RING1 Antibody detects endogenous levels of total RING1
Applications Notes
Western blot analysis of RING1 expression in Ramos cell lysate.
Host or Source
Rabbit
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