RNase L Rabbit monoclonal antibody

Product Specifications

Background

Endoribonuclease that functions in the interferon (IFN) antiviral response. In INF treated and virus infected cells, RNASEL probably mediates its antiviral effects through a combination of direct cleavage of single-stranded viral RNAs, inhibition of protein synthesis through the degradation of rRNA, induction of apoptosis, and induction of other antiviral genes.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Product Name Alternative

PRCA1; Ribonuclease4; RibonucleaseL; RNase L; Rnasel; RNS4

Swiss Prot

Q05823

Reactivity

Human

Immunogen

A synthesized peptide derived from human RNase L

Conjugation

Unconjugated

Applications

Dilution

WB 1:500~1:2000

Purity

Affinity-chromatography

Modification

Unmodified

Molecular Weight

80kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

RNase L Antibody detects endogenous levels of total RNase L

Applications Notes

Western blot analysis of RNase L expression in THP1 cell lysate.

Host or Source

Rabbit

Available Sizes

Curated Selection

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