RNase L Rabbit monoclonal antibody
Product Specifications
Background
Endoribonuclease that functions in the interferon (IFN) antiviral response. In INF treated and virus infected cells, RNASEL probably mediates its antiviral effects through a combination of direct cleavage of single-stranded viral RNAs, inhibition of protein synthesis through the degradation of rRNA, induction of apoptosis, and induction of other antiviral genes.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Product Name Alternative
PRCA1; Ribonuclease4; RibonucleaseL; RNase L; Rnasel; RNS4
Swiss Prot
Q05823
Reactivity
Human
Immunogen
A synthesized peptide derived from human RNase L
Conjugation
Unconjugated
Applications
WB
Dilution
WB 1:500~1:2000
Purity
Affinity-chromatography
Modification
Unmodified
Molecular Weight
80kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
RNase L Antibody detects endogenous levels of total RNase L
Applications Notes
Western blot analysis of RNase L expression in THP1 cell lysate.
Host or Source
Rabbit
Available Sizes
Curated Selection
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