TrkB Rabbit monoclonal antibody
Product Specifications
Background
Receptor for brain-derived neurotrophic factor (BDNF), neurotrophin-3 and neurotrophin-4/5 but not nerve growth factor (NGF) . Involved in the development and/or maintenance of the nervous system. This is a tyrosine-protein kinase receptor. Known substrates for the TRK receptors are SHC1, PI-3 kinase, and PLC-gamma-1.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Product Name Alternative
BDNF tropomyosine receptor kinase B; GP145 TrkB; GP145-TrkB/GP95-TrkB; GP95 TrkB; Neurotrophic receptor tyrosine kinase 2; Ntrk2; RATTRKB1; Tkrb; TRKB; TrkB tyrosine kinase; TRKB1; Tropomyosin related kinase B
Swiss Prot
P15209 (Mouse)
Reactivity
Mouse Rat
Immunogen
A synthesized peptide derived from human TrkB
Conjugation
Unconjugated
Applications
WB IHC IP
Dilution
WB 1:500~1:2000 IHC 1:50~1:200 IP 1:50
Purity
Affinity-chromatography
Modification
Unmodified
Molecular Weight
90,140kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
TrkB Antibody detects endogenous levels of total TrkB
Applications Notes
Western blot analysis of TrkB expression in mouse brain lysate.
Host or Source
Rabbit
Available Sizes
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