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TrkB Rabbit monoclonal antibody

Product Specifications

Background

Receptor for brain-derived neurotrophic factor (BDNF), neurotrophin-3 and neurotrophin-4/5 but not nerve growth factor (NGF) . Involved in the development and/or maintenance of the nervous system. This is a tyrosine-protein kinase receptor. Known substrates for the TRK receptors are SHC1, PI-3 kinase, and PLC-gamma-1.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Product Name Alternative

BDNF tropomyosine receptor kinase B; GP145 TrkB; GP145-TrkB/GP95-TrkB; GP95 TrkB; Neurotrophic receptor tyrosine kinase 2; Ntrk2; RATTRKB1; Tkrb; TRKB; TrkB tyrosine kinase; TRKB1; Tropomyosin related kinase B

Swiss Prot

P15209 (Mouse)

Reactivity

Mouse Rat

Immunogen

A synthesized peptide derived from human TrkB

Conjugation

Unconjugated

Applications

WB IHC IP

Dilution

WB 1:500~1:2000 IHC 1:50~1:200 IP 1:50

Purity

Affinity-chromatography

Modification

Unmodified

Molecular Weight

90,140kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

TrkB Antibody detects endogenous levels of total TrkB

Applications Notes

Western blot analysis of TrkB expression in mouse brain lysate.

Host or Source

Rabbit

Available Sizes

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