COPS3 Rabbit monoclonal antibody
Product Specifications
Background
Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Product Name Alternative
COP9 subunit 3; cops3; CSN3; JAB 1 containing signalosome subunit 3; SGN3; Signalosome subunit 3
Swiss Prot
Q9UNS2
Reactivity
Human Mouse Rat
Immunogen
A synthesized peptide derived from human COPS3
Conjugation
Unconjugated
Applications
WB ICC/IF IP FC
Dilution
WB 1:500~1:2000 ICC/IF 1:50~1:200 IP 1:50 FC 1:50
Purity
Affinity-chromatography
Modification
Unmodified
Molecular Weight
48 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
COPS3 Antibody detects endogenous levels of total COPS3
Applications Notes
Western blot analysis of COPS3 expression in HeLa cell lysate.
Host or Source
Rabbit
Available Sizes
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