U2AF65 Rabbit monoclonal antibody
Product Specifications
Background
Necessary for the splicing of pre-mRNA. Induces cardiac troponin-T (TNNT2) pre-mRNA exon inclusion in muscle. Regulates the TNNT2 exon 5 inclusion through competition with MBNL1. Binds preferentially to a single-stranded structure within the polypyrimidine tract of TNNT2 intron 4 during spliceosome assembly.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Product Name Alternative
HU2AF65; U2af2; U2AF65
Swiss Prot
P26368
Reactivity
Human Mouse Rat
Immunogen
A synthesized peptide derived from human U2AF65
Conjugation
Unconjugated
Applications
WB IHC ICC/IF
Dilution
WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200
Purity
Affinity-chromatography
Modification
Unmodified
Molecular Weight
54kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
U2AF65 Antibody detects endogenous levels of total U2AF65
Applications Notes
Western blot analysis of U2AF65 expression in Jurkat cell lysate.
Host or Source
Rabbit
Available Sizes
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