RNF40 Rabbit monoclonal antibody
Product Specifications
Background
E3 ubiquitin-protein ligase that mediates monoubiquitination of 'Lys-120' of histone H2B (H2BK120ub1) . H2BK120ub1 gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 'Lys-4' and 'Lys-79' methylation (H3K4me and H3K79me, respectively) .
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Product Name Alternative
BRE 1B; BRE1 B; BRE1B; RBP95; Rnf40; STARING
Swiss Prot
O75150
Reactivity
Mouse, Rat, Human
Immunogen
A synthesized peptide derived from human RNF40
Conjugation
Unconjugated
Applications
WB IHC IP
Dilution
WB 1:500~1:2000 IHC 1:50~1:200 IP 1:50
Purity
Affinity-chromatography
Modification
Unmodified
Molecular Weight
130kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
RNF40 Antibody detects endogenous levels of total RNF40
Applications Notes
Western blot analysis of RNF40 expression in (1) HeLa cell lysate; (2) RAW264.7 cell lysate.
Host or Source
Rabbit
Available Sizes
Curated Selection
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