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RNF40 Rabbit monoclonal antibody

Product Specifications

Background

E3 ubiquitin-protein ligase that mediates monoubiquitination of 'Lys-120' of histone H2B (H2BK120ub1) . H2BK120ub1 gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 'Lys-4' and 'Lys-79' methylation (H3K4me and H3K79me, respectively) .

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Product Name Alternative

BRE 1B; BRE1 B; BRE1B; RBP95; Rnf40; STARING

Swiss Prot

O75150

Reactivity

Mouse, Rat, Human

Immunogen

A synthesized peptide derived from human RNF40

Conjugation

Unconjugated

Applications

WB IHC IP

Dilution

WB 1:500~1:2000 IHC 1:50~1:200 IP 1:50

Purity

Affinity-chromatography

Modification

Unmodified

Molecular Weight

130kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

RNF40 Antibody detects endogenous levels of total RNF40

Applications Notes

Western blot analysis of RNF40 expression in (1) HeLa cell lysate; (2) RAW264.7 cell lysate.

Host or Source

Rabbit

Available Sizes

Curated Selection

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