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LIMK1 Rabbit monoclonal antibody

Product Specifications

Background

Protein kinase which regulates actin filament dynamics. Phosphorylates and inactivates the actin binding/depolymerizing factor cofilin, thereby stabilizing the actin cytoskeleton. Stimulates axonal outgrowth and may be involved in brain development. Isoform 3 has a dominant negative effect on actin cytoskeletal changes.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Product Name Alternative

LIM kinase; LIMK 1; LIMK

Swiss Prot

P53667

Reactivity

Human Mouse

Immunogen

A synthesized peptide derived from human LIM Kinase 1

Conjugation

Unconjugated

Applications

WB

Dilution

WB 1:500~1:2000

Purity

Affinity-chromatography

Modification

Unmodified

Molecular Weight

72kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

LIM Kinase 1 Antibody detects endogenous levels of total LIM Kinase 1

Applications Notes

Western blot analysis of LIM Kinase 1 expression in U-87MG cell lysate.

Host or Source

Rabbit

Available Sizes

Curated Selection

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