LIMK1 Rabbit monoclonal antibody
Product Specifications
Background
Protein kinase which regulates actin filament dynamics. Phosphorylates and inactivates the actin binding/depolymerizing factor cofilin, thereby stabilizing the actin cytoskeleton. Stimulates axonal outgrowth and may be involved in brain development. Isoform 3 has a dominant negative effect on actin cytoskeletal changes.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Product Name Alternative
LIM kinase; LIMK 1; LIMK
Swiss Prot
P53667
Reactivity
Human Mouse
Immunogen
A synthesized peptide derived from human LIM Kinase 1
Conjugation
Unconjugated
Applications
WB
Dilution
WB 1:500~1:2000
Purity
Affinity-chromatography
Modification
Unmodified
Molecular Weight
72kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
LIM Kinase 1 Antibody detects endogenous levels of total LIM Kinase 1
Applications Notes
Western blot analysis of LIM Kinase 1 expression in U-87MG cell lysate.
Host or Source
Rabbit
Available Sizes
Curated Selection
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