IL23 Rabbit monoclonal antibody
Product Specifications
Background
Associates with IL12B to form the IL-23 interleukin, an heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to an heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Product Name Alternative
IL 23A; IL 23p19; IL12B; IL23; Il23a; IL23P19; P19; SGRF
Swiss Prot
Q9NPF7
Reactivity
Human
Immunogen
A synthesized peptide derived from human IL23
Conjugation
Unconjugated
Applications
WB
Dilution
WB 1:500~1:1000
Purity
Affinity-chromatography
Modification
Unmodified
Molecular Weight
21kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IL23 Antibody detects endogenous levels of total IL23
Applications Notes
Western blot analysis of IL23 expression in Raji cell lysate.
Host or Source
Rabbit
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