Bub1 Rabbit monoclonal antibody
Product Specifications
Background
Serine/threonine-protein kinase that performs 2 crucial functions during mitosis: it is essential for spindle-assembly checkpoint signaling and for correct chromosome alignment. Has a key role in the assembly of checkpoint proteins at the kinetochore, being required for the subsequent localization of CENPF, BUB1B, CENPE and MAD2L1.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Product Name Alternative
Bub1; BUB1A; BUB1L; hBUB1
Swiss Prot
O43683
Reactivity
Human Mouse Rat
Immunogen
A synthesized peptide derived from human Bub1
Conjugation
Unconjugated
Applications
WB IHC
Dilution
WB 1:500~1:1000 IHC 1:50~1:200
Purity
Affinity-chromatography
Modification
Unmodified
Molecular Weight
122kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Bub1 Antibody detects endogenous levels of total Bub1
Applications Notes
Western blot analysis of Bub1 expression in K562 cell lysate.
Host or Source
Rabbit
Available Sizes
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