CoREST Rabbit monoclonal antibody
Product Specifications
Background
Essential component of the BHC complex, a corepressor complex that represses transcription of neuron-specific genes in non-neuronal cells. The BHC complex is recruited at RE1/NRSE sites by REST and acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Product Name Alternative
COREST; Nr2b2; RCOR; Rcor1; Rxrb
Swiss Prot
Q9UKL0
Reactivity
Human Mouse Rat
Immunogen
A synthesized peptide derived from human CoREST
Conjugation
Unconjugated
Applications
WB IHC ICC/IF
Dilution
WB 1:1000~1:5000 IHC 1:50~1:200 ICC/IF 1:50~1:200
Purity
Affinity-chromatography
Modification
Unmodified
Molecular Weight
66kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
CoREST Antibody detects endogenous levels of total CoREST
Applications Notes
Western blot analysis of CoREST expression in Molt-4 cell lysate.
Host or Source
Rabbit
Available Sizes
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