KMT5A / SETD8 / Pr-SET7 Rabbit monoclonal antibody
Product Specifications
Background
Protein-lysine N-methyltransferase that monomethylates both histones and non-histone proteins. Specifically monomethylates 'Lys-20' of histone H4 (H4K20me1) . H4K20me1 is enriched during mitosis and represents a specific tag for epigenetic transcriptional repression. Mainly functions in euchromatin regions, thereby playing a central role in the silencing of euchromatic genes.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Product Name Alternative
KMT5A; PR-Set7; SET07; SET8
Swiss Prot
Q9NQR1
Reactivity
Human Mouse Rat
Immunogen
A synthesized peptide derived from human KMT5A / SETD8 / Pr-SET7
Conjugation
Unconjugated
Applications
WB FC
Dilution
WB 1:1000~1:5000 FC 1:100
Purity
Affinity-chromatography
Modification
Unmodified
Molecular Weight
50kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
KMT5A / SETD8 / Pr-SET7 Antibody detects endogenous levels of total KMT5A / SETD8 / Pr-SET7
Applications Notes
Western blot analysis of KMT5A / SETD8 / Pr-SET7 expression in (1) 293T cell lysate; (2) NIH/3T3 cell lysate.
Host or Source
Rabbit
Available Sizes
Curated Selection
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