RNF8 Rabbit monoclonal antibody
Product Specifications
Background
Mediates the ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53BP1 and BRCA1 ionizing radiation-induced foci (IRIF) . Promotes the formation of 'Lys-63'-linked polyubiquitin chains and functions with the specific ubiquitin-conjugating UBE2N/UBC13.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Product Name Alternative
C3HC4 type zinc finger protein; RNF8
Swiss Prot
O76064
Reactivity
Human Rat
Immunogen
A synthesized peptide derived from human RNF8
Conjugation
Unconjugated
Applications
WB
Dilution
WB 1:500~1:2000
Purity
Affinity-chromatography
Modification
Unmodified
Molecular Weight
60kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
RNF8 Antibody detects endogenous levels of total RNF8
Applications Notes
Western blot analysis of RNF8 expression in human fetal kidney lysate.
Host or Source
Rabbit
Available Sizes
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