GABARAP Rabbit monoclonal antibody
Product Specifications
Background
GABARAP is cleaved at its carboxyl terminus, which leads to conjugation by either of the phospholipids phosphatidylethanolamine or phosphatidylserine. This processing converts GABARAP from a type I to a type II membrane bound form involved in autophagosome biogenesis. Processing of GABARAP involves cleavage by Atg4 family members followed by conjugation by the E1 and E2 like enzymes Atg7 and Atg3.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Product Name Alternative
GABARAP; GABARAPL1; GABARAPL2
Swiss Prot
O95166
Reactivity
Human Mouse Rat
Immunogen
A synthesized peptide derived from human GABARAP
Conjugation
Unconjugated
Applications
WB IHC ICC/IF FC
Dilution
WB 1:500~1:2000 IHC 1:100~1:500 ICC/IF 1:50~1:200 FC 1:50
Purity
Affinity-chromatography
Modification
Unmodified
Molecular Weight
17kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
GABARAP Antibody detects endogenous levels of total GABARAP
Applications Notes
Western blot analysis of GABARAP expression in (1) HepG2 cell lysate; (2) Mouse kidney lysate; (3) Rat heart lysate.
Host or Source
Rabbit
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