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OPA1 Rabbit monoclonal antibody

Product Specifications

Background

Dynamin-related GTPase required for mitochondrial fusion and regulation of apoptosis. May form a diffusion barrier for proteins stored in mitochondrial cristae. Proteolytic processing in response to intrinsic apoptotic signals may lead to disassembly of OPA1 oligomers and release of the caspase activator cytochrome C (CYCS) into the mitochondrial intermembrane space.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Product Name Alternative

Large GTP binding protein; largeG; MGM1; Mitochondrial dynamin like GTPase; NPG; NTG; OAK; OPA 1

Swiss Prot

O60313

Reactivity

Human Mouse Rat

Immunogen

A synthesized peptide derived from human OPA1

Conjugation

Unconjugated

Applications

WB IHC ICC/IF FC

Dilution

WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 FC 1:50

Purity

Affinity-chromatography

Modification

Unmodified

Molecular Weight

85kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

OPA1 Antibody detects endogenous levels of total OPA1

Applications Notes

Western blot analysis of OPA1 expression in HeLa cell lysate.

Host or Source

Rabbit

Available Sizes

Frequently Asked Questions

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