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MSin3A Rabbit monoclonal antibody

Product Specifications

Background

Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Also interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3A to DNA. Acts as a corepressor for REST.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Product Name Alternative

Histone deacetylase complex subunit Sin 3a; Paired amphipathic helix protein Sin 3a; SIN3 homolog A

Swiss Prot

Q96ST3

Reactivity

Human Mouse Rat

Immunogen

A synthesized peptide derived from human mSin3A

Conjugation

Unconjugated

Applications

WB IHC ICC/IF FC

Dilution

WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 FC 1:50

Purity

Affinity-chromatography

Modification

Unmodified

Molecular Weight

150kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

MSin3A Antibody detects endogenous levels of total mSin3A

Applications Notes

Western blot analysis of mSin3A expression in (1) K562 cell lysate; (2) RAW 264.7 cell lysate.

Host or Source

Rabbit

Available Sizes

Frequently Asked Questions

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