MSin3A Rabbit monoclonal antibody
Product Specifications
Background
Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Also interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3A to DNA. Acts as a corepressor for REST.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Product Name Alternative
Histone deacetylase complex subunit Sin 3a; Paired amphipathic helix protein Sin 3a; SIN3 homolog A
Swiss Prot
Q96ST3
Reactivity
Human Mouse Rat
Immunogen
A synthesized peptide derived from human mSin3A
Conjugation
Unconjugated
Applications
WB IHC ICC/IF FC
Dilution
WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 FC 1:50
Purity
Affinity-chromatography
Modification
Unmodified
Molecular Weight
150kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
MSin3A Antibody detects endogenous levels of total mSin3A
Applications Notes
Western blot analysis of mSin3A expression in (1) K562 cell lysate; (2) RAW 264.7 cell lysate.
Host or Source
Rabbit
Available Sizes
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