HEC1 Rabbit monoclonal antibody
Product Specifications
Background
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Product Name Alternative
HEC; HsHec1; hsNDC80; Kinetochore protein Hec1; Kinetochore-associated protein 2; KNTC2; ndc80; TID3
Swiss Prot
O14777
Reactivity
Human Mouse Rat
Immunogen
A synthesized peptide derived from human HEC1
Conjugation
Unconjugated
Applications
WB IP
Dilution
WB 1:1000~1:5000 IP 1:50
Purity
Affinity-chromatography
Modification
Unmodified
Molecular Weight
74kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
HEC1 Antibody detects endogenous levels of total HEC1
Applications Notes
Western blot analysis of HEC1 expression in Jurkat cell lysate.
Host or Source
Rabbit
Available Sizes
Curated Selection
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