ITK Rabbit monoclonal antibody
Product Specifications
Background
Interleukin-2 inducible T-cell kinase (Itk, Emt or Tsk) is a member of the non-receptor protein tyrosine kinases. Family members of Itk include Tec, Btk, Rlk and Bmx and are all defined by a common structure: an amino-terminal PH domain, a Tec-homology domain and a SH3 and SH2 domain followed by a carboxy-terminal kinase domain. Tec, Rlk and Itk are expressed in T cells and activated in response to T cell receptor (TCR) engagement.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Product Name Alternative
EMT; Homolog of mouse T cell itk/tsk; IL 2 inducible T cell kinase; Itk; Kinase EMT; LPFS1; LYK; PSCTK2; T cell specific kinase; TSK; Tyrosine protein kinase ITK/TSK
Swiss Prot
Q08881
Reactivity
Human
Immunogen
A synthesized peptide derived from human ITK
Conjugation
Unconjugated
Applications
WB IHC FC
Dilution
WB 1:500~1:2000 IHC 1:50~1:200 FC 1:60
Purity
Affinity-chromatography
Modification
Unmodified
Molecular Weight
72kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
ITK Antibody detects endogenous levels of total ITK
Applications Notes
Western blot analysis of ITK expression in Jurkat cell lysate.
Host or Source
Rabbit
Available Sizes
Curated Selection
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