ACVRL1 Rabbit monoclonal antibody
Product Specifications
Background
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for TGF-beta. May bind activin as well.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Product Name Alternative
SKR3; Activin receptor-like kinase 1; ALK-1; TGF-B superfamily receptor type I; TSR-I; ACVRL1; ACVRLK1; ALK1
Swiss Prot
P37023
Reactivity
Human Mouse Rat
Immunogen
A synthesized peptide derived from human ACVRL1
Conjugation
Unconjugated
Applications
WB
Dilution
WB 1:500~1:2000
Purity
Affinity-chromatography
Modification
Unmodified
Molecular Weight
56kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
ACVRL1 Antibody detects endogenous levels of total ACVRL1
Applications Notes
Western blot analysis of ACVRL1 expression in (1) Jurkat cell lysate; (2) Mouse kidney lysate; (3) Rat kidney lysate.
Host or Source
Rabbit
Available Sizes
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