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ACVRL1 Rabbit monoclonal antibody

Product Specifications

Background

On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for TGF-beta. May bind activin as well.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Product Name Alternative

SKR3; Activin receptor-like kinase 1; ALK-1; TGF-B superfamily receptor type I; TSR-I; ACVRL1; ACVRLK1; ALK1

Swiss Prot

P37023

Reactivity

Human Mouse Rat

Immunogen

A synthesized peptide derived from human ACVRL1

Conjugation

Unconjugated

Applications

WB

Dilution

WB 1:500~1:2000

Purity

Affinity-chromatography

Modification

Unmodified

Molecular Weight

56kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

ACVRL1 Antibody detects endogenous levels of total ACVRL1

Applications Notes

Western blot analysis of ACVRL1 expression in (1) Jurkat cell lysate; (2) Mouse kidney lysate; (3) Rat kidney lysate.

Host or Source

Rabbit

Available Sizes

Curated Selection

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