USP14 Rabbit monoclonal antibody
Product Specifications
Background
Ubiquitin-Specific Protease 14, which is also known as the 60 kDa subunit of tRNA-guanine transglycosylase (USP14/TGT60 kDa) . USP14 is recruited to the proteasome through its reversible association with the PSMD2 (S2/hRPN1) subunit of the 19S regulatory particle. Whereas PSMD14 appears to promote substrate degradation, USP14 is thought to antagonize substrate degradation.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Product Name Alternative
TGT; tRNA guanine transglycosylase 60 kD subunit; Ubiquitin carboxyl terminal hydrolase 14; Ubiquitin specific peptidase 14; USP14
Swiss Prot
P54578
Reactivity
Human Mouse Rat
Immunogen
A synthesized peptide derived from human USP14
Conjugation
Unconjugated
Applications
WB ICC/IF FC
Dilution
WB 1:500~1:2000 ICC/IF 1:50~1:200 FC 1:60
Purity
Affinity-chromatography
Modification
Unmodified
Molecular Weight
56kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
USP14 Antibody detects endogenous levels of total USP14
Applications Notes
Western blot analysis of USP14 expression in (1) HeLa cell lysate; (2) RAW 264.7 cell lysate; (3) C6 cell lysate.
Host or Source
Rabbit
Available Sizes
Frequently Asked Questions
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