HnRNP A1 Rabbit monoclonal antibody
Product Specifications
Background
HnRNP A1 regulates the alternative splicing of c-Src and c-H-Ras and modifies initiation of translation of the fibroblast growth factor 2 mRNA. hnRNP A1 expression level is elevated in many cancers; knockdown of hnRNP A1 leads to apoptosis in various cancer cells. Although predominantly nuclear, hnRNP A1 is continually transported from the nucleus to the cytoplasm where it disassociates from mRNA and is rapidly re-imported into the nucleus.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Product Name Alternative
HNRNPA 1; HNRNPA1; HNRPA1
Swiss Prot
P09651
Reactivity
Human Mouse Rat
Immunogen
A synthesized peptide derived from human hnRNP A1
Conjugation
Unconjugated
Applications
WB IHC ICC/IF FC
Dilution
WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 FC 1:50
Purity
Affinity-chromatography
Modification
Unmodified
Molecular Weight
33kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
HnRNP A1 Antibody detects endogenous levels of total hnRNP A1
Applications Notes
Western blot analysis of hnRNP A1 expression in HepG2 cell lysate.
Host or Source
Rabbit
Available Sizes
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