Leptin Receptor Rabbit monoclonal antibody
Product Specifications
Background
On ligand binding, mediates LEP central and peripheral effects through the activation of different signaling pathways such as JAK2/STAT3 and MAPK cascade/FOS. In the hypothalamus, LEP acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones (By similarity) .
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Product Name Alternative
Leptin receptor; LEP-R; HuB219 OB receptor; OB-R; CD295; LEPR; DB; OBR
Swiss Prot
P48357
Reactivity
Human Mouse Rat
Immunogen
A synthesized peptide derived from human Leptin Receptor
Conjugation
Unconjugated
Applications
WB
Dilution
WB 1:500~1:2000
Purity
Affinity-chromatography
Modification
Unmodified
Molecular Weight
150kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Leptin Receptor Antibody detects endogenous levels of total Leptin Receptor
Applications Notes
Western blot analysis of Leptin Receptor expression in SH-SY5Y cell lysate.
Host or Source
Rabbit
Available Sizes
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