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A2M Rabbit monoclonal antibody

Product Specifications

Background

Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It inhibits many proteases, including trypsin, thrombin and collagenase. A2M is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits.

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Product Name Alternative

A2m; Alpha 2M; Alpha-2-macroglobulin; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5; CPAMD5; FWP007; S863 7

Swiss Prot

P01023

Reactivity

Human

Immunogen

A synthesized peptide derived from human A2M

Conjugation

Unconjugated

Applications

WB IHC

Dilution

WB 1:500~1:2000 IHC 1:50~1:200

Purity

Affinity-chromatography

Modification

Unmodified

Molecular Weight

163kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

A2M Antibody detects endogenous levels of total A2M

Applications Notes

Western blot analysis of A2M expression in human plasma lysate.

Host or Source

Rabbit

CAS Number

9007-83-4

Available Sizes

Curated Selection

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