SMC3 Rabbit monoclonal antibody
Product Specifications
Background
Central component of cohesin, a complex required for chromosome cohesion during the cell cycle. The cohesin complex may form a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. Cohesion is coupled to DNA replication and is involved in DNA repair. The cohesin complex plays also an important role in spindle pole assembly during mitosis and in chromosomes movement.
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Product Name Alternative
SMC protein 3; Bamacan; SMC3; BAM; BMH; CSPG6; SMC3L1
Swiss Prot
Q9UQE7
Reactivity
Human Mouse Rat
Immunogen
A synthesized peptide derived from human SMC3
Conjugation
Unconjugated
Applications
WB IHC ICC/IF FC
Dilution
WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 FC 1:50
Purity
Affinity-chromatography
Modification
Unmodified
Molecular Weight
141kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
SMC3 Antibody detects endogenous levels of total SMC3
Applications Notes
Western blot analysis of SMC3 expression in HeLa cell lysate.
Host or Source
Rabbit
CAS Number
9007-83-4
Available Sizes
Curated Selection
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