Parkin Rabbit monoclonal antibody
Product Specifications
Background
Parkin is a zinc-finger protein that is related to ubiquitin at the amino terminus. May protect neurons against alpha synuclein toxicity, proteasomal dysfunction, GPR37 accumulation, and kainate-induced excitotoxicity. May play a role in controlling neurotransmitter trafficking at the presynaptic terminal and in calcium-dependent exocytosis. Regulates cyclin-E during neuronal apoptosis.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Product Name Alternative
AR-JP; LPRS2; PARK2; parkin; parkin 2; PDJ; PRKN; PRKN2
Swiss Prot
O60260
Reactivity
Human Mouse Rat
Immunogen
A synthesized peptide derived from human Parkin
Conjugation
Unconjugated
Applications
WB IHC ICC/IF IP FC
Dilution
WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50 FC 1:50
Purity
Affinity-chromatography
Modification
Unmodified
Molecular Weight
52kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Parkin Antibody detects endogenous levels of total Parkin
Applications Notes
Western blot analysis of Parkin expression in Jurkat cell lysate.
Host or Source
Rabbit
Available Sizes
Curated Selection
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