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Parkin Rabbit monoclonal antibody

Product Specifications

Background

Parkin is a zinc-finger protein that is related to ubiquitin at the amino terminus. May protect neurons against alpha synuclein toxicity, proteasomal dysfunction, GPR37 accumulation, and kainate-induced excitotoxicity. May play a role in controlling neurotransmitter trafficking at the presynaptic terminal and in calcium-dependent exocytosis. Regulates cyclin-E during neuronal apoptosis.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Product Name Alternative

AR-JP; LPRS2; PARK2; parkin; parkin 2; PDJ; PRKN; PRKN2

Swiss Prot

O60260

Reactivity

Human Mouse Rat

Immunogen

A synthesized peptide derived from human Parkin

Conjugation

Unconjugated

Applications

WB IHC ICC/IF IP FC

Dilution

WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50 FC 1:50

Purity

Affinity-chromatography

Modification

Unmodified

Molecular Weight

52kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

Parkin Antibody detects endogenous levels of total Parkin

Applications Notes

Western blot analysis of Parkin expression in Jurkat cell lysate.

Host or Source

Rabbit

Available Sizes

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