Phospho-STAT3 (Y705) Rabbit monoclonal antibody
Product Specifications
Background
The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Product Name Alternative
APRF; Stat3; HIES; Acute-phase response factor
Swiss Prot
P40763
Reactivity
Human Mouse Rat
Immunogen
A synthesized peptide derived from human STAT3
Conjugation
Unconjugated
Applications
WB IHC ICC/IF IP
Dilution
WB 1:5000~1:10000 IHC 1:50~1:100 ICC/IF 1:50~1:000 IP 1:30
Purity
Affinity-chromatography
Modification
Phosphorylated
Molecular Weight
88kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Phospho-STAT3 (Y705) Antibody detects endogenous levels of total Phospho-STAT3 (Y705)
Applications Notes
Western blot analysis of Phospho-STAT3 (Tyr705) expression in (1) HeLa cell lysate; (2) HeLa cell lysate treated with IFN-a.
Host or Source
Rabbit
Available Sizes
Frequently Asked Questions
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