Phospho-mTOR (S2481) Rabbit monoclonal antibody
Product Specifications
Background
An atypical kinase belonging to the PIKK family of kinases. Controls cell growth through protein synthesis regulation. Downstream of PI3K/Akt pathway and required for cell survival. Acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Product Name Alternative
FRAP; FRAP1; FRAP2; RAFT1; Rapamycin target protein; kinase mTOR
Swiss Prot
P42345
Reactivity
Human Mouse Rat
Immunogen
A synthesized peptide derived from human Phospho-mTOR (S2481)
Conjugation
Unconjugated
Applications
WB
Dilution
WB 1:500~1:2000
Purity
Affinity-chromatography
Modification
Phosphorylated
Molecular Weight
289kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Phospho-mTOR (S2481) Antibody detects endogenous levels of total Phospho-mTOR (S2481)
Applications Notes
Western blot analysis of Phospho-mTOR (S2481) expression in (1) 293 cell lysate treated with LP; (2) 293 cell lysate.
Host or Source
Rabbit
Available Sizes
Curated Selection
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