LC3B Rabbit monoclonal antibody
Product Specifications
Background
Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes) . Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Product Name Alternative
ATG8F; LC3B; MAP1LC3B; MLP3B; MAP1LC3B
Swiss Prot
Q9GZQ8
Reactivity
Human Mouse Rat
Immunogen
A synthesized peptide derived from human LC3B
Conjugation
Unconjugated
Applications
WB ICC/IF IP
Dilution
WB 1:500~1:2000 ICC/IF 1:50~1:200 IP 1:50
Purity
Affinity-chromatography
Modification
Unmodified
Molecular Weight
14,16kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
LC3B Antibody detects endogenous levels of total LC3B
Applications Notes
Western blot analysis of LC3B expression in (1) Human brain lysate; (2) RAW 264.7 cell lysate; (3) C6 cell lysate.
Host or Source
Rabbit
Available Sizes
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