PD-L1 (CD274) Rabbit monoclonal antibody
Product Specifications
Background
Programmed cell death ligand 1 (CD274, or B7-H1, PD-L1), is the first member of B7 family to be discovered. B7 family molecules are type I transmembrane proteins belonging to the immunoglobulin superfamily. In concert with their CD28 family receptors, the B7s are key regulators of the adaptive immune response. CD274 is suggested a negative regulator of T and B cell, and play important role in mediating tolerance of lymphocytes to self-antigens.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Product Name Alternative
B7-H; B7H1; PD-L1; PDCD1L1; PDCD1LG1; PDL1; CD274
Swiss Prot
Q9NZQ7
Reactivity
Human Mouse Rat
Immunogen
A synthesized peptide derived from human PD-L1 (CD274)
Conjugation
Unconjugated
Applications
WB IHC
Dilution
WB 1:100~1:500 IHC 1:50~1:100
Purity
Affinity-chromatography
Modification
Unmodified
Molecular Weight
46kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
PD-L1 (CD274) Antibody detects endogenous levels of total PD-L1 (CD274)
Applications Notes
Western blot analysis of PD-L1 (CD274) expression in Ramos cell lysate.
Host or Source
Rabbit
Available Sizes
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