JNK1/JNK3 Rabbit monoclonal antibody
Product Specifications
Background
The stress-activated protein kinase/Jun-amino-terminal kinase SAPK/JNK is potently and preferentially activated by a variety of environmental stresses including UV and gamma radiation, ceramides, inflammatory cytokines, and in some instances, by growth factors and GPCR agonists. As with the other MAPKs, the core signaling unit is composed of a MAPKKK, typically MEKK1-MEKK4, or by one of the mixed lineage kinases (MLKs), which phosphorylate and activate MKK4/7.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Product Name Alternative
C-Jun N-terminal kinase 3; FLJ12099; FLJ33785; JNK1; JNK3; JNK3 alpha protein kinase; JNK3A; MAP kinase 10; MAP kinase p49 3F12; MAPK 10; MAPK10
Swiss Prot
P45983/P53779
Reactivity
Human Mouse Rat
Immunogen
A synthesized peptide derived from human JNK1/JNK3
Conjugation
Unconjugated
Applications
WB IP
Dilution
WB 1:1000~1:2000 IP 1:50
Purity
Affinity-chromatography
Modification
Unmodified
Molecular Weight
46,54kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
JNK1/JNK3 Antibody detects endogenous levels of total JNK1/JNK3
Applications Notes
Western blot analysis of JNK1/JNK3 expression in HeLa cell lysate.
Host or Source
Rabbit
Available Sizes
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