Phospho-Rac1/Cdc42 (Ser71) Rabbit monoclonal antibody
Product Specifications
Background
Rac and Cdc42 are members of the Rho-GTPase family. In mammals, Rac exists as three isoforms, Rac1, Rac2 and Rac3, which are highly similar in sequence. Rac1 and Cdc42, the most widely studied of this group, are ubiquitously expressed. Rac2 is expressed in cells of hematopoietic origin, and Rac3, while highly expressed in brain, is also found in many other tissues. Rac and Cdc42 play key signaling roles in cytoskeletal reorganization, membrane trafficking, transcriptional regulation, cell growth and development.
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Product Name Alternative
CDC42; CDC42Hs; G25K; TKS; MIG5; Ras like protein TC25
Swiss Prot
P60953/P63000
Reactivity
Human
Immunogen
A synthesized peptide derived from human Phospho-Rac1/Cdc42 (Ser71)
Conjugation
Unconjugated
Applications
WB
Dilution
WB 1:500~1:1000
Purity
Affinity-chromatography
Modification
Phosphorylated
Molecular Weight
24kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Phospho-Rac1/Cdc42 (Ser71) Antibody detects endogenous levels of total Phospho-Rac1/Cdc42 (Ser71)
Applications Notes
Western blot analysis of Phospho-Rac1/Cdc42 (Ser71) expression in (1) A431 cell lysate treated with LP; (2) A431 cell lysate.
Host or Source
Rabbit
CAS Number
9007-83-4
Available Sizes
Curated Selection
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