Phospho-Cdc6 (S54) Rabbit monoclonal antibody
Product Specifications
Background
Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated.Cdc6 has recently been shown to play an important role in the intra-S-phase p21 Waf1/Cip1-dependent DNA damage response. Both cdc6 and CDT1 are degraded by the ubiquitin proteasome pathway in response to DNA damage associated with re-replication.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Product Name Alternative
CDC6; CDC18L; CDC6-related protein; Cdc18-related protein; HsCDC6; HsCDC18; p62 (cdc6)
Swiss Prot
Q99741
Reactivity
Human
Immunogen
A synthesized peptide derived from human Phospho-Cdc6 (S54)
Conjugation
Unconjugated
Applications
WB ICC/IF
Dilution
WB 1:500~1:1000 ICC/IF 1:50~1:200
Purity
Affinity-chromatography
Modification
Phosphorylated
Molecular Weight
63kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Phospho-Cdc6 (S54) Antibody detects endogenous levels of total Phospho-Cdc6 (S54)
Applications Notes
Western blot analysis of Phospho-Cdc6 (S54) expression in (1) Raji cell lysate; (2) Raji + FBS cell lysate.
Host or Source
Rabbit
Available Sizes
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