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TrkA+B+C Rabbit monoclonal antibody

Product Specifications

Background

The family of Trk receptor tyrosine kinases consists of TrkA, TrkB, and TrkC. While the sequence of these family members is highly conserved, they are activated by different neurotrophins: TrkA by NGF, TrkB by BDNF or NT4, and TrkC by NT3. Neurotrophin signaling through these receptors regulates a number of physiological processes, such as cell survival, proliferation, neural development, and axon and dendrite growth and patterning.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Product Name Alternative

Gp140trk; GP145-TrkB; GP145-TrkC; MTC; NTRK1; NTRK2; NTRK3; p140-TrkA; TRKA; TRKB; TrkB tyrosine kinase; TRKC

Swiss Prot

P04629/Q16288/Q16620

Reactivity

Human Mouse Rat

Immunogen

A synthesized peptide derived from human TrkA+B+C

Conjugation

Unconjugated

Applications

WB IHC ICC/IF

Dilution

WB 1:1000~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200

Purity

Affinity-chromatography

Modification

Unmodified

Molecular Weight

140kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

TrkA+B+C Antibody detects endogenous levels of TrkA+B+C

Applications Notes

Western blot analysis of TrkA+B+C expression in Human fetal brain lysate.

Host or Source

Rabbit

Available Sizes

Curated Selection

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