HDAC4 Rabbit monoclonal antibody
Product Specifications
Background
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4) . Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Product Name Alternative
Histone deacetylase 4; HD4; HDAC4; AHO3; BDMR
Swiss Prot
P56524
Reactivity
Human
Immunogen
A synthesized peptide derived from human HDAC4
Conjugation
Unconjugated
Applications
WB ICC/IF
Dilution
WB 1:1000~1:2000 ICC/IF 1:50~1:200
Purity
Affinity-chromatography
Modification
Unmodified
Molecular Weight
140kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
HDAC4 Antibody detects endogenous levels of HDAC4
Applications Notes
Western blot analysis of HDAC4 expression in Hela lysate.
Host or Source
Rabbit
Available Sizes
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