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HDAC4 Rabbit monoclonal antibody

Product Specifications

Background

Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4) . Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Product Name Alternative

Histone deacetylase 4; HD4; HDAC4; AHO3; BDMR

Swiss Prot

P56524

Reactivity

Human

Immunogen

A synthesized peptide derived from human HDAC4

Conjugation

Unconjugated

Applications

WB ICC/IF

Dilution

WB 1:1000~1:2000 ICC/IF 1:50~1:200

Purity

Affinity-chromatography

Modification

Unmodified

Molecular Weight

140kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

HDAC4 Antibody detects endogenous levels of HDAC4

Applications Notes

Western blot analysis of HDAC4 expression in Hela lysate.

Host or Source

Rabbit

Available Sizes

Frequently Asked Questions

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