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HDAC7 Rabbit monoclonal antibody

Product Specifications

Background

Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4) . Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer factors such as MEF2A, MEF2B and MEF2C.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Product Name Alternative

HD 7a; HD7; HDAC 7; HDAC 7A; Hdac7; HDAC7A; Histone deacetylase 7; Histone deacetylase 7A

Swiss Prot

Q8WUI4

Reactivity

Human Mouse Rat

Immunogen

A synthesized peptide derived from human HDAC7

Conjugation

Unconjugated

Applications

WB FC

Dilution

WB 1:1000~1:2000 FC 1:100

Purity

Affinity-chromatography

Modification

Unmodified

Molecular Weight

124kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

HDAC7 Antibody detects endogenous levels of HDAC7

Applications Notes

Western blot analysis of HDAC7 expression in HeLa cell lysate.

Host or Source

Rabbit

Available Sizes

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