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Phospho-AMPK alpha 2 (S345) Rabbit monoclonal antibody

Product Specifications

Background

AMP-activated protein kinase (AMPK) is highly conserved from yeast to plants and animals and plays a key role in the regulation of energy homeostasis. AMPK is a heterotrimeric complex composed of a catalytic α subunit and regulatory β and γ subunits, each of which is encoded by two or three distinct genes (α1, 2; β1, 2; γ1, 2, 3) . The kinase is activated by an elevated AMP/ATP ratio due to cellular and environmental stress, such as heat shock, hypoxia, and ischemia.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Product Name Alternative

ACACA kinase; Acetyl-CoA carboxylase kinase; AMPK subunit alpha-2; AMPK2; AMPKalpha2; HMGCR kinase; Hydroxymethylglutaryl-CoA reductase kinase; PRKAA; PRKAA2

Swiss Prot

P54646

Reactivity

Human Mouse Rat

Immunogen

A synthesized peptide derived from human AMPK alpha 2

Conjugation

Unconjugated

Applications

WB

Dilution

WB 1:1000~1:2000

Purity

Affinity-chromatography

Modification

Phosphorylated

Molecular Weight

64kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

Phospho-AMPK alpha 2 (S345) Antibody detects endogenous levels of Phospho-AMPK alpha 2 (S345)

Applications Notes

Western blot analysis of Phospho-AMPK alpha 2 (S345) expression in (1) 293T cell lysate treated with Lambda Phosphatase; (2) 293T cell lysate.

Host or Source

Rabbit

Available Sizes

Frequently Asked Questions

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