Phospho-AMPK alpha 2 (S345) Rabbit monoclonal antibody
Product Specifications
Background
AMP-activated protein kinase (AMPK) is highly conserved from yeast to plants and animals and plays a key role in the regulation of energy homeostasis. AMPK is a heterotrimeric complex composed of a catalytic α subunit and regulatory β and γ subunits, each of which is encoded by two or three distinct genes (α1, 2; β1, 2; γ1, 2, 3) . The kinase is activated by an elevated AMP/ATP ratio due to cellular and environmental stress, such as heat shock, hypoxia, and ischemia.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Product Name Alternative
ACACA kinase; Acetyl-CoA carboxylase kinase; AMPK subunit alpha-2; AMPK2; AMPKalpha2; HMGCR kinase; Hydroxymethylglutaryl-CoA reductase kinase; PRKAA; PRKAA2
Swiss Prot
P54646
Reactivity
Human Mouse Rat
Immunogen
A synthesized peptide derived from human AMPK alpha 2
Conjugation
Unconjugated
Applications
WB
Dilution
WB 1:1000~1:2000
Purity
Affinity-chromatography
Modification
Phosphorylated
Molecular Weight
64kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Phospho-AMPK alpha 2 (S345) Antibody detects endogenous levels of Phospho-AMPK alpha 2 (S345)
Applications Notes
Western blot analysis of Phospho-AMPK alpha 2 (S345) expression in (1) 293T cell lysate treated with Lambda Phosphatase; (2) 293T cell lysate.
Host or Source
Rabbit
Available Sizes
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