MEK7 Rabbit monoclonal antibody
Product Specifications
Background
MKK7 is strongly activated by TNF-α, as well as other environmental stresses, whereas SEK1/MKK4, which activates both p38 and SAPK/JNK pathways, is not activated by TNF-α. Sequence alignment of the activation loop of the MAP kinase kinase family members indicates that Ser271 and Thr275 are potential phosphorylation sites that are crucial for the kinase acivity.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Product Name Alternative
MKK7; Jnkk2; MAPKK7; PRKMK7; JNK-activating kinase 2; MAPKK 7; Mitogen Activated Protein Kinase kinase 7; SAPKK4; stress-activated protein kinase kinase 4
Swiss Prot
O14733
Reactivity
Human Mouse Rat
Immunogen
A synthesized peptide derived from human MEK7
Conjugation
Unconjugated
Applications
WB IHC ICC/IF IP FC
Dilution
WB 1:1000~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:40 FC 1:50
Purity
Affinity-chromatography
Modification
Unmodified
Molecular Weight
47kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
MEK7 Antibody detects endogenous levels of MEK7
Applications Notes
Western blot analysis of MEK5 expression in Hela cell lysate.
Host or Source
Rabbit
Available Sizes
Curated Selection
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