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MEK7 Rabbit monoclonal antibody

Product Specifications

Background

MKK7 is strongly activated by TNF-α, as well as other environmental stresses, whereas SEK1/MKK4, which activates both p38 and SAPK/JNK pathways, is not activated by TNF-α. Sequence alignment of the activation loop of the MAP kinase kinase family members indicates that Ser271 and Thr275 are potential phosphorylation sites that are crucial for the kinase acivity.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Product Name Alternative

MKK7; Jnkk2; MAPKK7; PRKMK7; JNK-activating kinase 2; MAPKK 7; Mitogen Activated Protein Kinase kinase 7; SAPKK4; stress-activated protein kinase kinase 4

Swiss Prot

O14733

Reactivity

Human Mouse Rat

Immunogen

A synthesized peptide derived from human MEK7

Conjugation

Unconjugated

Applications

WB IHC ICC/IF IP FC

Dilution

WB 1:1000~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:40 FC 1:50

Purity

Affinity-chromatography

Modification

Unmodified

Molecular Weight

47kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

MEK7 Antibody detects endogenous levels of MEK7

Applications Notes

Western blot analysis of MEK5 expression in Hela cell lysate.

Host or Source

Rabbit

Available Sizes

Frequently Asked Questions

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