ERK5 Rabbit monoclonal antibody
Product Specifications
Background
Erk5 (Mitogen-activated protein kinase 7, Big mitogen-activated protein kinase 1) is a member of the MAPK superfamily implicated in the regulation numerous cellular processes including proliferation, differentiation, and survival. In neuronal cells, Erk5 is required for NGF-induced neurite outgrowth, neuronal homeostasis, and survival. Erk5 is thought to play a role in blood vessel integrity via maintenance of endothelial cell migration and barrier function.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Product Name Alternative
Big MAP kinase 1; BMK 1; BMK 1 kinase; BMK-1; BMK1; BMK1 Kinase; ERK 4; ERK 5; ERK-5; ERK4; ERK5; MAP kinase 7; MAPK 7; Mitogen Activated Protein Kinase
Swiss Prot
Q13164
Reactivity
Human Mouse Rat
Immunogen
A synthesized peptide derived from human ERK5
Conjugation
Unconjugated
Applications
WB ICC/IF IP FC
Dilution
WB 1:1000~1:2000 ICC/IF 1:50~1:200 IP 1:50 FC 1:50
Purity
Affinity-chromatography
Modification
Unmodified
Molecular Weight
115kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
ERK5 Antibody detects endogenous levels of ERK5
Applications Notes
Western blot analysis of ERK5 expression in Hela cell lysate.
Host or Source
Rabbit
Available Sizes
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