Phospho-SIRT1 (T530) Rabbit monoclonal antibody
Product Specifications
Background
The Silent Information Regulator (SIR2) family of genes is a highly conserved group of genes that encode nicotinamide adenine dinucleotide (NAD) -dependent protein deacetylases, also known as class III histone deacetylases. SirT1 deacetylase activity is inhibited by nicotinamide and activated by resveratrol.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Product Name Alternative
NAD-dependent protein deacetylase sirtuin-1; hSIRT1; Regulatory protein SIR2 homolog 1; SIR2-like protein 1; hSIR2; SirtT1 75 kDa fragment; 75SirT1; SIRT1; SIR2L1
Swiss Prot
Q96EB6
Reactivity
Human
Immunogen
A synthesized peptide derived from human SIRT1
Conjugation
Unconjugated
Applications
WB
Dilution
WB 1:1000~1:2000
Purity
Affinity-chromatography
Modification
Phosphorylated
Molecular Weight
120kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Phospho-SIRT1 (T530) Antibody detects endogenous levels of Phospho-SIRT1 (T530)
Applications Notes
Western blot analysis of Phospho-SIRT1 (T530) expression in (1) 293T cell lysate; (2) 293T cell treated with Calyculin A.
Host or Source
Rabbit
Available Sizes
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